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Incidence, Characteristics and Implications of Thromboembolic Events in Patients with Muscle Invasive Urothelial Carcinoma of the Bladder Undergoing Neoadjuvant Chemotherapy

Duivenvoorden WC, Daneshmand S, Canter D, Lotan Y, Black PC, Abdi H, et al.

J Urol. 2016 Dec;196(6):1627-1633

Editorial comment from Piotr Chlosta: The overall incidence of thromboembolic events (TEEs) in patients undergoing neoadjuvant chemotherapy before radical cystectomy was 14%, with 58% of events occurring preoperatively. Prophylaxis to prevent TEEs may need to be initiated earlier in these patients, during the NAC treatment course.