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Long-term outcomes among patients who achieve complete or near-complete responses after the induction phase of bladder-preserving combined modality therapy for muscle-invasive bladder cancer: A pooled analysis of RTOG 9906 and 0233

Journal of Clinical Oncology (2014) 32:4 SUPPL. 1.

Journal of Clinical Oncology (2014) 32:4 SUPPL. 1.

Comment from Maria Ribal: Bladder preserving strategies could be assumed in very well selected patients affected by muscle invasive bladder cancer. Trimodality therapy (including maximal TURb, radiotherapy and concomitant chemotherapy) is the recommended option when planning a bladder sparing approach.
For TURb assessing response to chemo-radiation therapy it is crucial to select patients that should be rescued by cystectomy and those that can be maintained in the program. Absence of tumor in TURb (T0) or minimal diseases (Ta or Tis) can be considered for bladder preservation therapy in those selected cases.