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Nivolumab in metastatic urothelial carcinoma after platinum therapy (CheckMate 275): a multicentre, single-arm, phase 2 trial
Sharma P, Retz M, Siefker-Radtke A, Baron A, Necchi A, Bedke J, et al.Category: Bladder
Editorial comment from Piotr Chlosta: In patients with metastatic or surgically unresectable advanced urothelial carcinoma with progression or recurrent disease despite first line platinum-based chemotherapy, PD-1 inhibitor nivolumab monotherapy was associated with meaningful clinical benefit, regardless of PD-L1 expression.
Efficacy of Systemic Chemotherapy Plus Radical Nephroureterectomy for Metastatic Upper Tract Urothelial CarcinomaCategory: Bladder
Editorial comment from Piotr Chlosta: Results suggest that radical nephroureterectomy in addition to systemic chemotherapy may improve overall survival in patients with metastatic upper tract urothelial carcinoma.